Specific Cell Targeting by <i>Toxoplasma gondii</i> Displaying Functional Single-Chain Variable Fragment as a Novel Strategy; A Proof of Principle

Specific Cell Targeting by <i>Toxoplasma gondii</i> Displaying Functional Single-Chain Variable Fragment as a Novel Strategy; A Proof of Principle

<i>Toxoplasma gondii</i> holds significant therapeutic potential; however, its nonspecific invasiveness results in off-target effects. The purpose of this study is to evaluate whether <i>T. gondii</i> specificity can be improved by surface display of scFv directed against den...

Full description

Bibliographic Details
Main Authors: Muna Aljieli, Clément Rivière, Louis Lantier, Nathalie Moiré, Zineb Lakhrif, Anne-France Boussemart, Thomas Cnudde, Laurie Lajoie, Nicolas Aubrey, Elhadi M. Ahmed, Isabelle Dimier-Poisson, Anne Di-Tommaso, Marie-Noëlle Mévélec
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Cells
Subjects:
<i>Toxoplasma gondii</i>
surface display
targeting
scFv
cancer immunotherapy
immune checkpoint
Online Access:https://www.mdpi.com/2073-4409/13/11/975

Internet

https://www.mdpi.com/2073-4409/13/11/975

Similar Items