The Relationship between Reactive Oxygen Species and the cGAS/STING Signaling Pathway in the Inflammaging Process

The Relationship between Reactive Oxygen Species and the cGAS/STING Signaling Pathway in the Inflammaging Process

During Inflammaging, a dysregulation of the immune cell functions is generated, and these cells acquire a senescent phenotype with an increase in pro-inflammatory cytokines and ROS. This increase in pro-inflammatory molecules contributes to the chronic inflammation and oxidative damage of biomolecul...

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Bibliographic Details
Main Authors: Bárbara Andrade, Carlos Jara-Gutiérrez, Marilyn Paz-Araos, Mary Carmen Vázquez, Pablo Díaz, Paola Murgas
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
inflammaging
ROS
cGAS/STING pathway
cGAS
STING
immunosenescence
Online Access:https://www.mdpi.com/1422-0067/23/23/15182

Internet

https://www.mdpi.com/1422-0067/23/23/15182

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