Sirtuin1 Mediates the Protective Effects of Echinacoside against Sepsis-Induced Acute Lung Injury via Regulating the NOX4-Nrf2 Axis

Sirtuin1 Mediates the Protective Effects of Echinacoside against Sepsis-Induced Acute Lung Injury via Regulating the NOX4-Nrf2 Axis

Currently, the treatment for sepsis-induced acute lung injury mainly involves mechanical ventilation with limited use of drugs, highlighting the urgent need for new therapeutic options. As a pivotal aspect of acute lung injury, the pathologic activation and apoptosis of endothelial cells related to...

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Bibliographic Details
Main Authors: Weixi Xie, Lang Deng, Miao Lin, Xiaoting Huang, Rui Qian, Dayan Xiong, Wei Liu, Siyuan Tang
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Antioxidants
Subjects:
echinacoside
SIRT1
oxidative stress
acute lung injury
NOX4
Nrf2
Online Access:https://www.mdpi.com/2076-3921/12/11/1925

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https://www.mdpi.com/2076-3921/12/11/1925

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