Resistance of hypervirulent Klebsiella pneumoniae to cathepsin B-mediated pyroptosis in murine macrophages

Resistance of hypervirulent Klebsiella pneumoniae to cathepsin B-mediated pyroptosis in murine macrophages

IntroductionHypervirulent Klebsiella pneumoniae (hvKp) has emerged as a clinically significant global pathogen in the last decade. However, the host immune responses of the macrophages during hvKp infection are largely unknown. In the present study, we aimed to compare the cytotoxic effects of hvKp...

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Bibliographic Details
Main Authors: Jin Kyung Kim, Hui-Jung Jung, Miri Hyun, Ji Yeon Lee, Jong-Hwan Park, Seong-Il Suh, Won-Ki Baek, Hyun ah Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
hypervirulent
Klebsiella pneumoniae
macrophages
pyroptosis
cathepsin B
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1207121/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1207121/full

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