Reduced Ca2+ transient amplitudes may signify increased or decreased depolarization depending on the neuromodulatory signaling pathway

Reduced Ca2+ transient amplitudes may signify increased or decreased depolarization depending on the neuromodulatory signaling pathway

Neuromodulators regulate neuronal excitability and bias neural circuit outputs. Optical recording of neuronal Ca2+ transients is a powerful approach to study the impact of neuromodulators on neural circuit dynamics. We are investigating the polymodal nociceptor ASH in Caenorhabditis elegans to bette...

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Bibliographic Details
Main Authors: Arunima Debnath, Paul D. E. Williams, Bruce A. Bamber
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Neuroscience
Subjects:
neuromodulation
Ca2+ dynamics
depolarization
signal integration
graded potentials
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.931328/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.931328/full

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