A Method to Combine Neurofilament Light Measurements From Blood Serum and Plasma in Clinical and Population-Based Studies

A Method to Combine Neurofilament Light Measurements From Blood Serum and Plasma in Clinical and Population-Based Studies

IntroductionNeurofilament light (NfL) can be detected in blood of healthy individuals and at elevated levels in those with different neurological diseases. We investigated if the choice of biological matrix can affect results when using NfL as biomarker in epidemiological studies.MethodWe obtained p...

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Bibliographic Details
Main Authors: Nicole Rübsamen, Eline A. J. Willemse, David Leppert, Heinz Wiendl, Matthias Nauck, André Karch, Jens Kuhle, Klaus Berger
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neurology
Subjects:
agreement
beta coefficient
biomarker
neurofilament
SiMoA
Z-score standardization
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.894119/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.894119/full

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