Dynamic Features of Chromosomal Instability during Culture of Induced Pluripotent Stem Cells

Dynamic Features of Chromosomal Instability during Culture of Induced Pluripotent Stem Cells

Induced pluripotent stem cells (iPSCs) hold great potential for regenerative medicine. By reprogramming a patient′s own cells, immunological rejection can be avoided during transplantation. For expansion and gene editing, iPSCs are grown in artificial culture for extended times. Culture affords pote...

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Bibliographic Details
Main Authors: Casey O. DuBose, John R. Daum, Christopher L. Sansam, Gary J. Gorbsky
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Genes
Subjects:
aneuploidy
mitosis
trisomy
chromosome 12
optical mapping
structural variants
Online Access:https://www.mdpi.com/2073-4425/13/7/1157

Internet

https://www.mdpi.com/2073-4425/13/7/1157

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