Kynurenic acid, a key L-tryptophan-derived metabolite, protects the heart from an ischemic damage

<h4>Background</h4> Renal injury induces major changes in plasma and cardiac metabolites. Using a small- animal in vivo model, we sought to identify a key metabolite whose levels are significantly modified following an acute kidney injury (AKI) and to analyze whether this agent could off...

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Bibliographic Details
Main Authors: Einat Bigelman, Metsada Pasmanik-Chor, Bareket Dassa, Maxim Itkin, Sergey Malitsky, Orly Dorot, Edward Pichinuk, Yuval Kleinberg, Gad Keren, Michal Entin-Meer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449225/?tool=EBI