Metformin Protects Radiation-Induced Early Brain Injury by Reducing Inflammation and DNA Damage

Radiation-induced brain injury (RIBI) is one of the most common and fatal complications of cranial radiation therapy (CRT); however, no effective intervention is available currently. Metformin has been reported to have anti-RIBI activity as a first-line anti-diabetic drug. However, the mechanism of...

Full description

Bibliographic Details
Main Authors: Jiabao Xiang, Yiming Lu, Cheng Quan, Yan Gao, Gangqiao Zhou
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/13/4/645