Metformin Protects Radiation-Induced Early Brain Injury by Reducing Inflammation and DNA Damage

Metformin Protects Radiation-Induced Early Brain Injury by Reducing Inflammation and DNA Damage

Radiation-induced brain injury (RIBI) is one of the most common and fatal complications of cranial radiation therapy (CRT); however, no effective intervention is available currently. Metformin has been reported to have anti-RIBI activity as a first-line anti-diabetic drug. However, the mechanism of...

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Bibliographic Details
Main Authors: Jiabao Xiang, Yiming Lu, Cheng Quan, Yan Gao, Gangqiao Zhou
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Brain Sciences
Subjects:
metformin
radiation
radiation-induced brain injury
Online Access:https://www.mdpi.com/2076-3425/13/4/645

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