Autophagy-independent enhancing effects of Beclin 1 on cytotoxicity of ovarian cancer cells mediated by proteasome inhibitors

Autophagy-independent enhancing effects of Beclin 1 on cytotoxicity of ovarian cancer cells mediated by proteasome inhibitors

<p>Abstract</p> <p>Background</p> <p>The ubiquitin-proteasome system and macroautophagy (hereafter referred to autophagy) are two complementary pathways for protein degradation. Emerging evidence suggests that proteasome inhibition might be a promising approach for tumo...

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Bibliographic Details
Main Authors: Liu Chuan, Yan Xu, Wang Hua-Qin, Gao Yan-Yan, Liu Juanjuan, Hu Zhenhua, Liu Dawo, Gao Jian, Lin Bei
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Cancer
Subjects:
Proteasome inhibition
Beclin1
Ovarian cancer
Online Access:http://www.biomedcentral.com/1471-2407/12/622

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http://www.biomedcentral.com/1471-2407/12/622

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