Proteome Exploration of Legionella pneumophila To Identify Novel Therapeutics: a Hierarchical Subtractive Genomics and Reverse Vaccinology Approach

Proteome Exploration of Legionella pneumophila To Identify Novel Therapeutics: a Hierarchical Subtractive Genomics and Reverse Vaccinology Approach

ABSTRACT Legionella pneumophila is the causative agent of a severe type of pneumonia (lung infection) called Legionnaires’ disease. It is emerging as an antibiotic-resistant strain day by day. Hence, identifying novel drug targets and vaccine candidates is essential to fight against this pathogen. H...

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Bibliographic Details
Main Authors: Md Tahsin Khan, Araf Mahmud, Mahmudul Hasan, Kazi Faizul Azim, Musammat Kulsuma Begum, Mohimenul Haque Rolin, Arzuba Akter, Shakhinur Islam Mondal
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
Legionella pneumophila
Legionnaires’ disease
molecular dynamics
protein-protein docking
reverse vaccinology
subtractive genomics
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00373-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00373-22

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