Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice

Abstract Long-term potentiation (LTP) is a key cellular mechanism for learning and memory, and recent studies in the hippocampus found that LTP was impaired in aged animals. Previous studies of cortical LTP have focused primarily on the homosynaptic plasticity in adult mice, while fewer studies have...

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Bibliographic Details
Main Authors: Si-Bo Zhou, Man Xue, Weiqi Liu, Yu-Xin Chen, Qi-Yu Chen, Jing-Shan Lu, Jinjun Wang, Keqiang Ye, Xu-Hui Li, Min Zhuo
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-022-00992-x