Tumor Necrosis Factor-α G-308A Polymorphism and Sporadic IgA Nephropathy: A Meta-Analysis Using a Genetic Model-Free Approach

Tumor necrosis factor-α (TNF-α) is a potent pro-inflammatory cytokine, involved in the pathogenesis and progression of immunoglobulin A nephropathy (IgAN). A bi-allelic polymorphism in the promoter region, at position -308 (G/A) of the <i>TNF</i>-<i>α</i> gene (rs1800629) is...

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Bibliographic Details
Main Authors: Maria Tziastoudi, Ioanna Chronopoulou, Georgios Pissas, Christos Cholevas, Theodoros Eleftheriadis, Ioannis Stefanidis
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/7/1488