Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel

Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel

The sigma-1 receptor is a 223 amino acids molecular chaperone with a single transmembrane domain. It is resident to eukaryotic mitochondrial-associated endoplasmic reticulum and plasma membranes. By chaperone-mediated interactions with ion channels, G-protein coupled receptors and cell-signaling mol...

Full description

Bibliographic Details
Main Authors: Kang Zhang, Zhe Zhao, Liting Lan, Xiaoli Wei, Liyun Wang, Xiaoyan Liu, Haitao Yan, Jianquan Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Pharmacology
Subjects:
sigma-1 receptor
N-type Ca2+ channel
electrophysiology
ion channels modulation
protein–protein interaction
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00302/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00302/full

Similar Items