Insights into the genomic and functional divergence of NAT gene family to serve microbial secondary metabolism

Insights into the genomic and functional divergence of NAT gene family to serve microbial secondary metabolism

Abstract Microbial NAT enzymes, which employ acyl-CoA to acylate aromatic amines and hydrazines, have been well-studied for their role in xenobiotic metabolism. Some homologues have also been linked to secondary metabolism, but this function of NAT enzymes is not as well-known. For this comparative...

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Main Authors: Sotiria Boukouvala, Evanthia Kontomina, Ioannis Olbasalis, Dionysios Patriarcheas, Dimosthenis Tzimotoudis, Konstantina Arvaniti, Aggelos Manolias, Maria-Aggeliki Tsatiri, Dimitra Basdani, Sokratis Zekkas
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-65342-4

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https://doi.org/10.1038/s41598-024-65342-4

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