Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury

Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury

Abstract This study was designed to test the hypothesis that in addition to repairing the architectural and cellular cues via regenerative medicine, the delivery of immune cues (immunotherapy) may be needed to enhance regeneration following volumetric muscle loss (VML) injury. We identified IL-10 si...

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Bibliographic Details
Main Authors: Tai Huynh, Cassandra Reed, Zain Blackwell, Payton Phelps, Luis C. Pinzon Herrera, Jorge Almodovar, David A. Zaharoff, Jeffrey Wolchok
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-27981-x

Internet

https://doi.org/10.1038/s41598-023-27981-x

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