Rates of CTL killing in persistent viral infection in vivo.
The CD8+ cytotoxic T lymphocyte (CTL) response is an important defence against viral invasion. Although CTL-mediated cytotoxicity has been widely studied for many years, the rate at which virus-infected cells are killed in vivo by the CTL response is poorly understood. To date the rate of CTL killin...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-04-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3974637?pdf=render |