Hepatoprotective Effect of Oplopanax elatus Nakai Adventitious Roots Extract by Regulating CYP450 and PPAR Signaling Pathway

Hepatoprotective Effect of Oplopanax elatus Nakai Adventitious Roots Extract by Regulating CYP450 and PPAR Signaling Pathway

O. elatus Nakai is a traditional medicine that has been confirmed to exert effective antioxidant and anti-inflammatory functions, and is used for the treatment of different disorders. However, its potential beneficial effects on drug induced hepatotoxicity and relevant molecular mechanisms remain un...

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Bibliographic Details
Main Authors: Xiao-Long Jiang, Pan-Yue Luo, Yan-Ying Zhou, Zhi-Hui Luo, Yue-Jun Hao, Ming-Zhi Fan, Xiao-Han Wu, Hao Gao, Hui-Chang Bi, Zhi-Bin Zhao, Mei-Lan Lian, Zhe-Xiong Lian
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
Oplopanax elatus Nakai
adventitious roots
CYP450
neutrophil
PPAR
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.761618/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.761618/full

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