Purkinje Cardiomyocytes of the Adult Ventricular Conduction System Are Highly Diploid but Not Uniquely Regenerative

Purkinje Cardiomyocytes of the Adult Ventricular Conduction System Are Highly Diploid but Not Uniquely Regenerative

Adult hearts are characterized by inefficient regeneration after injury, thus, the features that support or prevent cardiomyocyte (CM) proliferation are important to clarify. Diploid CMs are a candidate cell type that may have unique proliferative and regenerative competence, but no molecular marker...

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Bibliographic Details
Main Authors: Hirofumi Watanabe, Ge Tao, Peiheng Gan, Baylee C. Westbury, Kristie D. Cox, Kelsey Tjen, Ruolan Song, Glenn I. Fishman, Takako Makita, Henry M. Sucov
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
polyploidy
diploid cardiomyocyte
heart regeneration
conduction system
Purkinje cell
Online Access:https://www.mdpi.com/2308-3425/10/4/161

Internet

https://www.mdpi.com/2308-3425/10/4/161

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