Matrix Metalloproteinase Mediated Type I Collagen Degradation — An Independent Risk Factor for Mortality in Women

Matrix Metalloproteinase Mediated Type I Collagen Degradation — An Independent Risk Factor for Mortality in Women

Chronic fibro-proliferative diseases are associated with nearly 45% of all deaths in the developed world. Matrix metalloproteinase (MMP) mediated remodeling of the extracellular matrix (ECM) plays an important role in disease development. Degradation of type I collagen is considered having a major r...

Full description

Bibliographic Details
Main Authors: K. Dragsbæk, J.S. Neergaard, H.B. Hansen, I. Byrjalsen, P. Alexandersen, S.N. Kehlet, A.-C. Bay-Jensen, C. Christiansen, M.A. Karsdal
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:EBioMedicine
Subjects:
Extracellular matrix remodeling
Clinical
Type I collagen
Mortality
MMP
Protease activity
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415300049

Internet

http://www.sciencedirect.com/science/article/pii/S2352396415300049

Similar Items