Pharmacogenomics Testing in Phase I Oncology Clinical Trials: Constructive Criticism Is Warranted

While over ten-thousand phase I studies are published in oncology, fewer than 1% of these studies stratify patients based on genetic variants that influence pharmacology. Pharmacogenetics-based patient stratification can improve the success of clinical trials by identifying responsive patients who h...

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Bibliographic Details
Main Authors: Tristan M. Sissung, William D. Figg
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/5/1131