Unaltered Fungal Burden and Lethality in Human CEACAM1-Transgenic Mice During Candida albicans Dissemination and Systemic Infection

Unaltered Fungal Burden and Lethality in Human CEACAM1-Transgenic Mice During Candida albicans Dissemination and Systemic Infection

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1, CD66a) is a receptor for Candida albicans. It is crucial for the immune response of intestinal epithelial cells to this opportunistic pathogen. Moreover, CEACAM1 is of importance for the mucosal colonization by different bacterial p...

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Bibliographic Details
Main Authors: Esther Klaile, Mario M. Müller, Cristina Zubiría-Barrera, Saskia Brehme, Tilman E. Klassert, Magdalena Stock, Adrian Durotin, Tien D. Nguyen, Sabina Feer, Bernhard B. Singer, Peter F. Zipfel, Sven Rudolphi, Ilse D. Jacobsen, Hortense Slevogt
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
carcinoembryonic antigen-related cell adhesion molecule 1
Candida albicans
colonization
dissemination
candidiasis mouse model
bone marrow-derived neutrophils
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02703/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.02703/full

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