IGF-binding protein 2 (IGFBP2) – oncogene or tumour suppressor?

The role of Insulin-like growth factor binding protein 2 (IGFBP2) in cancer is unclear. In general IGFBP2 is considered to be oncogenic and its expression is often observed to be elevated in cancer. However, there are a number of conflicting reports in vitro and in vivo where IGFBP2 acts in a tumour...

Full description

Bibliographic Details
Main Authors: Adam ePickard, Dennis J McCance
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00025/full