High Sensitivity of Circulating Tumor Cells Derived from a Colorectal Cancer Patient for Dual Inhibition with AKT and mTOR Inhibitors

High Sensitivity of Circulating Tumor Cells Derived from a Colorectal Cancer Patient for Dual Inhibition with AKT and mTOR Inhibitors

Circulating tumor cells (CTCs) are cells shed from the primary tumor into the bloodstream. While many studies on solid tumor cells exist, data on CTCs are scarce. The mortality of cancer is mostly associated with metastasis and recent research identified CTCs as initiators of metastasis. The PI3K/AK...

Full description

Bibliographic Details
Main Authors: Daniel J. Smit, Laure Cayrefourcq, Marie-Therese Haider, Nico Hinz, Klaus Pantel, Catherine Alix-Panabières, Manfred Jücker
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
circulating tumor cells
CTCs
drug sensitivity assays
PI3K/AKT/mTOR pathway
AKT
MK2206
Online Access:https://www.mdpi.com/2073-4409/9/9/2129

Internet

https://www.mdpi.com/2073-4409/9/9/2129

Similar Items