αvβ3 Integrin induces partial EMT independent of TGF-β signaling
Kariya, Oyama et al. propose that αvβ3 can drive a partial EMT phenotype characterized by maintained E-cadherin expression and upregulation of mesenchymal markers. This hybrid EMT state is independent of TGF-β1 signaling and characterised by increased migration, invasion, tumor cell proliferation, s...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02003-6 |