Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor)

Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor)

Abstract A lasting imbalance between fatty acid synthesis and consumption leads to non-alcoholic fatty liver disease (NAFLD), coupled with hepatitis and insulin resistance. Yet the details of the underlying mechanisms are not fully understood. Here, we unraveled that the expression of the transcript...

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Bibliographic Details
Main Authors: Lei Zhang, Jiabing Chen, Xiaoying Yang, Chuangpeng Shen, Jiawen Huang, Dong Zhang, Naihua Liu, Chaonan Liu, Yadi Zhong, Yingjian Chen, Kaijia Tang, Jingyi Guo, Tianqi Cui, Siwei Duan, Jiayu Li, Shangyi Huang, Huafeng Pan, Huabing Zhang, Xiaoqiang Tang, Yongsheng Chang, Yong Gao
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01727-7

Internet

https://doi.org/10.1038/s41392-023-01727-7

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