Ochratoxin A: In Utero Exposure in Mice Induces Adducts in Testicular DNA

Ochratoxin A: In Utero Exposure in Mice Induces Adducts in Testicular DNA

Ochratoxin A (OTA) is a nephrotoxin and carcinogen that is associated with Balkan endemic nephropathy and urinary tract tumors. OTA crosses the placenta and causes adducts in the liver and kidney DNA of newborns. Because the testis and kidney develop from the same embryonic tissue, we reasoned that...

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Bibliographic Details
Main Authors: Jamie E. Jennings-Gee, Mariana Tozlovanu, Richard Manderville, Mark Steven Miller, Annie Pfohl-Leszkowicz, Gary G. Schwartz
Format: Article
Language:English
Published: MDPI AG 2010-06-01
Series:Toxins
Subjects:
ochratoxin
testicular cancer
DNA adduct
transplacental contamination
epidemiology
Online Access:http://www.mdpi.com/2072-6651/2/6/1428/

Internet

http://www.mdpi.com/2072-6651/2/6/1428/

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