Identification of Recurrent Chromosome Breaks Underlying Structural Rearrangements in Mammary Cancer Cell Lines

Cancer genomes are characterized by the accumulation of small-scale somatic mutations as well as large-scale chromosomal deletions, amplifications, and complex structural rearrangements. This characteristic is at least partially dependent on the ability of cancer cells to undergo recurrent chromosom...

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Bibliographic Details
Main Authors: Natalie C. Senter, Andrew McCulley, Vladimir A. Kuznetsov, Wenyi Feng
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/7/1228