Identification of Tumor Mutation Burden and Immune Infiltrates in Hepatocellular Carcinoma Based on Multi-Omics Analysis

Identification of Tumor Mutation Burden and Immune Infiltrates in Hepatocellular Carcinoma Based on Multi-Omics Analysis

We aimed to explore the tumor mutational burden (TMB) and immune infiltration in HCC and investigate new biomarkers for immunotherapy. Transcriptome and gene mutation data were downloaded from the GDC portal, including 374 HCC samples and 50 matched normal samples. Furthermore, we divided the sample...

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Bibliographic Details
Main Authors: Lu Yin, Liuzhi Zhou, Rujun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
hepatocellular carcinoma
immune infiltration
tumor mutation burden
biomarkers
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.599142/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2020.599142/full

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