Specific inhibitor of Smad3 (SIS3) alleviated submandibular gland fibrosis and dysfunction after dominant duct ligation in mice

Background/purpose: Chronic obstructive sialadenitis (COS) is a condition that severely reduced patients’ quality of life. This study aimed to analyze the effects of SIS3, a specific inhibitor of small mothers against decapentaplegic 3 (SMAD3), on the submandibular gland (SMG) dysfunction, fibrosis,...

Full description

Bibliographic Details
Main Authors: Honglin Li, Guanru Wang, Minqi Hu, Runnan Dai, Chunjie Li, Yubin Cao
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Journal of Dental Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790223000417