Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer

Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer

Gastrin-releasing peptide receptor (GRPR) is overexpressed in the majority of prostate cancers. This study aimed to investigate the potential of <sup>64</sup>Cu (radionuclide for late time-point PET-imaging) for imaging of GRPR expression using NOTA-PEG<sub>2</sub>-RM26 and N...

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Bibliographic Details
Main Authors: Christina Baun, Bogdan Mitran, Sara S. Rinne, Johan H. Dam, Birgitte B. Olsen, Vladimir Tolmachev, Anna Orlova, Helge Thisgaard
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
gastrin-releasing peptide receptor
RM26
NOTA
NODAGA
bombesin antagonist
Co-55
Online Access:https://www.mdpi.com/1420-3049/25/24/5993

Internet

https://www.mdpi.com/1420-3049/25/24/5993

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