Gyrification patterns in first-episode, drug-naïve major depression: Associations with plasma levels of brain-derived neurotrophic factor and psychiatric symptoms

Gyrification patterns in first-episode, drug-naïve major depression: Associations with plasma levels of brain-derived neurotrophic factor and psychiatric symptoms

Background and objectivesCortical structural changes in major depressive disorder (MDD) are usually studied using a voxel-based morphometry approach to delineate the cortical gray matter volume. Among cortical structures, gyrification patterns are considered a relatively stable indicator. In this st...

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Bibliographic Details
Main Authors: Tomoya Natsuyama, Naomichi Okamoto, Keita Watanabe, Enkhmurun Chibaatar, Hirofumi Tesen, Gaku Hayasaki, Atsuko Ikenouchi, Shingo Kakeda, Reiji Yoshimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Psychiatry
Subjects:
gyrification
major depression
brain-derived neurotrophic factor
gray matter
cerebral cortex
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1031386/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1031386/full

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