Modulation of the mechanical properties of ventricular extracellular matrix hydrogels with a carbodiimide crosslinker and investigation of their cellular compatibility

Hydrogels made from the cardiac extracellular matrix (ECM) as two-dimensional (2D) or 3D cell-culture substrates have beneficial biochemical effects on the differentiation of stem cells into cardiomyocytes. The mechanical properties of the substrates that match those of the host tissues have been id...

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Bibliographic Details
Main Authors: Kyohei Fujita, Zhonggang Feng, Daisuke Sato, Tadashi Kosawada, Takao Nakamura, Yasuyuki Shiraishi, Misuo Umezu
Format: Article
Language:English
Published: AIMS Press 2018-01-01
Series:AIMS Materials Science
Subjects:
Online Access:http://www.aimspress.com/Materials/article/1802/fulltext.html