Enhanced dengue vaccine virus replication and neutralizing antibody responses in immune primed rhesus macaques
Abstract Antibody-dependent enhancement (ADE) is suspected to influence dengue virus (DENV) infection, but the role ADE plays in vaccination strategies incorporating live attenuated virus components is less clear. Using a heterologous prime-boost strategy in rhesus macaques, we examine the effect of...
| 主要な著者: | , , , , , , , , , , , , , , , |
|---|---|
| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Nature Portfolio
2021-05-01
|
| シリーズ: | npj Vaccines |
| オンライン･アクセス: | https://doi.org/10.1038/s41541-021-00339-y |