Ciprofloxacin-Induced Antibacterial Activity Is Atteneuated by Pretreatment with Antioxidant Agents

Ciprofloxacin works through interfering with replication and transcription of bacterial DNA, which leads to increased oxidative stress, and death of bacterial cells. Drugs with strong antioxidant such as tempol, melatonin and pentoxifylline might interfere with the antibacterial activity of ciproflo...

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Bibliographic Details
Main Authors: Majed M. Masadeh, Karem H. Alzoubi, Sayer I. Al-azzam, Omar F. Khabour, Ahlam M. Al-buhairan
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Pathogens
Subjects:
Online Access:http://www.mdpi.com/2076-0817/5/1/28