Macrophage-based therapy for intervertebral disc herniation: preclinical proof-of-concept

Abstract Intervertebral disc (IVD) degeneration and herniation is a leading cause of disability globally and a large unmet clinical need. No efficient non-surgical therapy is available, and there is an urgency for minimally invasive therapies capable of restoring tissue function. IVD spontaneous her...

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Bibliographic Details
Main Authors: Cláudia Ribeiro-Machado, Susana G. Santos, Inês A. Amaral, Joana Caldeira, Paulo Pereira, Mário A. Barbosa, Carla Cunha
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-023-00309-z