Proteinase K-pretreated ConA-based ELISA assay: a novel urine LAM detection strategy for TB diagnosis

Proteinase K-pretreated ConA-based ELISA assay: a novel urine LAM detection strategy for TB diagnosis

ObjectivesLipoarabinomannan (LAM), an abundant cell wall glycolipid of mycobacteria including Mycobacterium tuberculosis (Mtb), is a promising TB diagnostic marker. The current commercially available urine LAM assays are not sufficiently sensitive, and more novel detection strategies are urgently ne...

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Bibliographic Details
Main Authors: Huan Huang, Rong Qu, Kang Wu, Jinchuan Xu, Jianhui Li, Shuihua Lu, Guodong Sui, Xiao-Yong Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium tuberculosis
LAM
ConA
ELISA
urine
proteinase K
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1236599/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1236599/full

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