A network of regulations by small noncoding RNAs: the P TEFb kinase in development and pathology

A network of regulations by small noncoding RNAs: the P TEFb kinase in development and pathology

Part of the heterodimeric PTEF-b element of the PolII transcription machinery, the Cdk9 kinase plays a critical role in gene expression. Phosphorylation of several residues in the polymerase is required for elongation of transcript. It determines the rates of transcription and thus, plays a critical...

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Bibliographic Details
Main Authors: Hossein eGhanbarian, Valerie eGrandjean, Francois eCuzin, Minoo eRassoulzadegan
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Genetics
Subjects:
Heredity
Mice
epigenetic
noncoding RNA
cardiac hypertrophy
7sk
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2011.00095/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2011.00095/full

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