Discovery of Simple Diacylhydrazine-Functionalized Cinnamic Acid Derivatives as Potential Microtubule Stabilizers

To develop novel microtubule-binding agents for cancer therapy, an array of <i>N</i>-cinnamoyl-<i>N</i>’-(substituted)acryloyl hydrazide derivatives were facilely synthesized through a two-step process. Initially, the antiproliferative activity of these title compounds was ex...

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Bibliographic Details
Main Authors: Xiang Zhou, Yi-Hong Fu, Ya-Yu Zou, Jiao Meng, Gui-Ping Ou-Yang, Qiang-Sheng Ge, Zhen-Chao Wang
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/20/12365