Weighted Gene Co-Expression Network Analysis Reveals Key Genes and Potential Drugs in Abdominal Aortic Aneurysm

Weighted Gene Co-Expression Network Analysis Reveals Key Genes and Potential Drugs in Abdominal Aortic Aneurysm

Abdominal aortic aneurysm (AAA) is a prevalent aortic disease that causes high mortality due to asymptomatic gradual expansion and sudden rupture. The underlying molecular mechanisms and effective pharmaceutical therapy for preventing AAA progression have not been fully identified. In this study, we...

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Bibliographic Details
Main Authors: Ke-Jia Kan, Feng Guo, Lei Zhu, Prama Pallavi, Martin Sigl, Michael Keese
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
abdominal aortic aneurysm
weighted gene co-expression network
key module
hub gene
functional enrichment
drug–gene prediction
Online Access:https://www.mdpi.com/2227-9059/9/5/546

Internet

https://www.mdpi.com/2227-9059/9/5/546

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