Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer

Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer

Recurrence and metastasis are the main causes of triple-negative breast cancer (TNBC) mortality. On the basis of our clinical cohorts and integrative omics analyses, we hypothesized that understanding the interplay between fatty acid binding protein (FABP) and epoxy-eicosatrienoic acid (EET) driven...

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Bibliographic Details
Main Authors: Maria Karmella Apaya, Pei-Wen Hsiao, Yu-Chih Yang, Lie-Fen Shyur
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
triple-negative breast cancer
tumor relapse
metastasis
fatty acid binding protein
phytogalactolipid
doxorubicin
Online Access:https://www.mdpi.com/2072-6694/12/1/199

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https://www.mdpi.com/2072-6694/12/1/199

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