Genetic characterization of a novel organoid from human malignant giant-cell tumor

Genetic characterization of a novel organoid from human malignant giant-cell tumor

Malignant giant-cell tumors are extremely rare bone sarcomas that transform from conventional giant-cell tumors during long periods of treatment. Owing to their rarity, no further analysis of their molecular pathogenesis exists, and thus, no standard treatment has been established. Recently, organoi...

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Bibliographic Details
Main Authors: Rie Suzuki, Toru Wakamatsu, Keiichi Yoshida, Yukiko Matsuoka, Haruna Takami, Sho Nakai, Hironari Tamiya, Shigeki Kakunaga, Toshinari Yagi, Ken-ichi Yoshida, Yoshinori Imura, Yoshihiro Yui, Satoru Sasagawa, Satoshi Takenaka
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Journal of Bone Oncology
Subjects:
Malignant giant-cell tumor
Organoid
Xenograft
Bone sarcomas
H3-3A G34W mutation
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137423000192

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http://www.sciencedirect.com/science/article/pii/S2212137423000192

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