Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank [version 1; referees: 2 approved]

Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank [version 1; referees: 2 approved]

Background: Cognitive ability is a heritable trait with a polygenic architecture, for which several associated variants have been identified using genotype-based and candidate gene approaches. Haplotype-based analyses are a complementary technique that take phased genotype data into account, and pot...

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Bibliographic Details
Main Authors: David M. Howard, Mark J. Adams, Toni-Kim Clarke, Eleanor M. Wigmore, Yanni Zeng, Saskia P. Hagenaars, Donald M. Lyall, Pippa A. Thomson, Kathryn L. Evans, David J. Porteous, Reka Nagy, Caroline Hayward, Chris S. Haley, Blair H. Smith, Alison D. Murray, G. David Batty, Ian J. Deary, Andrew M. McIntosh
Format: Article
Language:English
Published: Wellcome 2017-08-01
Series:Wellcome Open Research
Subjects:
Cognitive Neuroscience
Online Access:https://wellcomeopenresearch.org/articles/2-61/v1

Internet

https://wellcomeopenresearch.org/articles/2-61/v1

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