Mapping the preclinical to clinical evidence and development trajectory of the oncolytic virus talimogene laherparepvec (T-VEC): a systematic review

Objective This study aimed to conduct a systematic review of preclinical and clinical evidence to chart the successful trajectory of talimogene laherparepvec (T-VEC) from the bench to the clinic.Design This study was a systematic review. The primary outcome of interest was the efficacy of treatment,...

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Bibliographic Details
Main Authors: Dean A Fergusson, Claire Butler, Manoj Lalu, Garvin J Leung, Yuan Yi Dong, Joshua Montroy, Rebecca C Auer
Format: Article
Language:English
Published: BMJ Publishing Group 2019-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/12/e029475.full