Unlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathway

Abstract STAM Binding Protein Like 1 (STAMBPL1), functions as a deubiquitinase (DUB) and plays a significant role in various types of cancers. However, its effect as a DUB participating in the HCC tumorigenesis and progression still unknown. In the study, the upregulation and strong prognosis value...

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Bibliographic Details
Main Authors: Zhihuai Wang, Yinjie Zhang, Yuhang Shen, Haiyang Zhou, Yuan Gao, Chunfu Zhu, Xihu Qin
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Biology Direct
Online Access:https://doi.org/10.1186/s13062-024-00460-7