Anti-VCAM-1 and Anti-IL4Rα Aptamer-Conjugated Super Paramagnetic Iron Oxide Nanoparticles for Enhanced Breast Cancer Diagnosis and Therapy

Anti-VCAM-1 and Anti-IL4Rα Aptamer-Conjugated Super Paramagnetic Iron Oxide Nanoparticles for Enhanced Breast Cancer Diagnosis and Therapy

The surface protein overexpressed on cancer cells can be used as biomarkers for early detection of specific diseases. Anti-VCAM-1 and anti-IL4Rα DNA aptamers specific to VCAM-1 and IL4Rα receptors that are overexpressed in 4T1 tumor-bearing mice could be used as potential biomarker for both diagnost...

Full description

Bibliographic Details
Main Authors: Raja Chinnappan, Achraf Al Faraj, Anas M. Abdel Rahman, Khalid M. Abu-Salah, Fouzi Mouffouk, Mohammed Zourob
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
VCAM1 aptamer
IL4Rα aptamer
luciferase assay
tumor imaging
MRI
BLI and SPION
Online Access:https://www.mdpi.com/1420-3049/25/15/3437

Internet

https://www.mdpi.com/1420-3049/25/15/3437

Similar Items