Cellular stress increases DRIP production and MHC Class I antigen presentation

BackgroundDefective ribosomal products (DRiPs) are non-functional proteins rapidly degraded during or after translation being an essential source for MHC class I ligands. DRiPs are characterized to derive from a substantial subset of nascent gene products that degrade more rapidly than their corresp...

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Bibliographic Details
Main Authors: Natalie Pach, Michael Basler
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1445338/full