Targeting the Cell Cycle, RRM2 and NF-κB for the Treatment of Breast Cancers

A hallmark of cancer is the dysregulation of the cell cycle. The CDK4/6 inhibitor palbociclib is approved for treating advanced estrogen-receptor-positive breast cancer, but its success is limited by the development of acquired resistance owing to long-term therapy despite promising clinical outcome...

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Bibliographic Details
Main Authors: Nahid Sultana, Howard L. Elford, Jesika S. Faridi
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/5/975