Further Extension of Lifespan by <i>Unc-43/CaMKII</i> and <i>Egl-8/PLCβ</i> Mutations in Germline-Deficient <i>Caenorhabditis elegans</i>
Reduction of insulin/insulin-like growth factor 1 (IGF1) signaling (IIS) promotes longevity across species. In the nematode <i>Caenorhabditis elegans</i>, ablation of germline stem cells (GSCs) and activity changes of the conserved signaling mediators <i>unc-43/CaMKII</i> (ca...
Main Authors: | Hildegard I. D. Mack, Laura G. Buck, Sonja Skalet, Jennifer Kremer, Hao Li, Elisabeth K. M. Mack |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/11/22/3527 |
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